
个人简介:
2010-14:北京化工大学,学士
2014-17:四川大学,硕士,导师顾忠伟教授
2017-20:南京工业大学,博士,导师周廉院士、顾忠伟教授
2020-23:南京大学医学院附属鼓楼医院,博士后,合作导师孙凌云教授
2023-至今:安徽医科大学第一附属医院,副研究员
研究方向:
生物医用高分子,纳米材料,工程化干细胞
联系方式:
hfzhu@ahmu.edu.cn
主持课题:
1. 国家自然科学基金青年项目,32401109,程序化响应炎症微环境的病毒仿生纳米体系用于狼疮性肾炎的精准协同治疗,2025-01至2027-12,30万元,在研,主持;
2. 安徽省高校科研项目重点项目,2024AH050830,ECM仿生的工程化MSCs减轻系统性硬化症纤维化机制的研究, 2025-01至2026-12,10万元,在研,主持;
3. 安徽省转化医学研究院科研基金培育项目,2023zhyx-C18,工程化干细胞减轻系统性硬化症纤维化的分子机制和临床转化研究,2024-01至2026-12,8万元,在研,主持;
4. 江苏省自然科学基金青年项目,BK20210016,基于树状多肽大分子的多功能水凝胶微球包裹MSCs及治疗SLE的探索研究,2021-07至2024-06,20万元,结题,主持。
代表性论文:
1. Zhu H.; Huang D.; Nie M.; Zhao, Y.; Sun, L., Dexamethasone loaded DNA scavenger nanogel for systemic lupus erythematosus treatment. Bioactive Materials, 2025, 43: 330-339.
2. Zhu, H.; Huang, D.; Wang, J.; Zhao, Y.; Sun, L., Viral Mimicking Polyplexes as Hierarchical Unpacking Vectors for Rheumatoid Arthritis Treatment. Advanced Science, 2024, 11 (32), e2402888.
3. Zhu, H.; Kong, B.; Che J.; Zhao Y.; Sun L., Bioinspired nanogels as cell-free DNA trapping and scavenging organelles for rheumatoid arthritis treatment. Proc Natl Acad Sci U S A, 2023, 120 (33), e2303385120
4. Zhu, H.; Wu, X.; Liu, R.; Zhao Y.; Sun L., ECM-Inspired Hydrogels with ADSCs Encapsulation for Rheumatoid Arthritis Treatment. Advanced Science, 2023, 2206253
5. Zhu, H.; Kong, B.; Nie, M.; Zhao, C.; Liu, R.; Xie, Y.; Zhao, Y.; Sun, L., ECM-inspired peptide dendrimer microgels with human MSCs encapsulation for systemic lupus erythematosus treatment. Nano Today, 2022, 43, 101454
6. Zhu, H.; Liu, R.; Shang, Y.; Sun, L., Polylysine complexes and their biomedical applications. Engineered Regeneration, 2023, 4 (1), 20-27
7. Zhu, H.; Xu, G.; Mao, H.; He, Y.; Gu Z., A Bioinspired Tissue Adhesive based on Hyperbranched Peptide with Fast and Strong Wet Adhesion. Advanced Healthcare Materials, 2022, 11, 2200874
8. Zhu, H.; Mei, X.; Mao, H.; He, Y.; Gu Z., Fast and High Strength Soft Tissue Bioadhesives based on a Peptide Dendrimer with Antimicrobial Properties and Hemostatic Ability. ACS Applied Materials & Interfaces, 2020, 12, 4241−4253
9. Zhu, H.; Tian, J.; Mao, H.; He, Y.; Gu Z., Bioadhesives for soft tissue sealing and healing. Current Opinion in Biomedical Engineering. 2021, 18:100271.
10. Zhu, H.; Cai, X.; Wu, L; Gu Z., A facile one-step gelation approach simultaneously combining physical and chemical cross-linking for the preparation of injectable hydrogels. Journal of Materials Chemistry B, 2017, 5, 3145